Glen Pyle

Dr. Glen Pyle

Email: 
gpyle@uoguelph.ca
Summary: 

Our laboratory is interested in the molecular basis of heart failure, and the development of novel therapies for the treatment of heart attacks and chronic heart failure.

Program

Biomedical Sciences

About my research

Our laboratory is interested in the molecular basis of heart failure, and the development of novel therapies for the treatment of heart attacks and chronic heart failure. We are investigating the mechanisms by which menopause increases the risk of heart disease in women, and sex differences in heart function. Together our research covers causes, molecular mechanisms, and treatments of heart disease.

How my research can improve life

Ischemic heart disease is the single largest cause of death among non-infectious diseases globally. While the ability to survive a heart attack has increased significantly with improved care, long term outcomes remain poor due to chronic heart failure. Among the groups with the fastest growing rates of ischemic heart disease is young women. Our research into the molecular basis of ischemic heart failure alongside investigations of sex differences in heart function allows us to develop novel strategies and treatments for this global threat to human health.

Why chose Biomedical Sciences at U of G?

The broad scope of our research interests from molecule to patient, and from mouse to dog to human, provides a comprehensive education and research training experience. Graduates of our laboratory have gone on to careers in academia, medicine, industry, government, and a number of other healthcare professions. Graduate research in the Department of Biomedical Sciences provides a strong foundation for future careers in a number of high demand areas.