I found being in a graduate university environment to be very beneficial for having access to experts on many topics. I would encourage new graduate students to not be afraid to reach out to various professors and other graduate students that can help guide you and offer advice.
My advice would be that a Masters degree is like a roller coaster. You will have your ups and downs in your research but that is all apart of being a scientist! There is no such thing as a 'bad' discovery.
If you are considering graduate studies, I suggest that you take your research interests and see who on campus is pursuing something that aligns with them. Given the wide range of topics and fields of study here, I would not be surprised to see at least one other individual or faculty member engaged in some research that closely mirrors the interests of the student.
I would advise a prospective graduate student to do their homework before contacting prospective advisors. Check out their profile on the University website, read their most recent paper, and even reach out to a senior graduate student currently in the lab!
My first piece advice to prospective grad students would be to find a lab or an advisor that you mesh well with and are excited about working with. If you are on the same page and feel comfortable from the start, it makes all the difference. After that, trust yourself and your abilities! You are capable of more than you think.
I've been very privileged and lucky since coming to Guelph for my undergraduate degree back in 2010 as all of the opportunities I have been given have been gained through building strong relationships with faculty and staff on campus and finding mentors that have helped guide me along my career path. I've always found that the people on campus are incredibly giving and willing to devote their time to help out students. I've also found that simply starting with expressing an interest to be more involved and showing initiative can go a very long way to opening doors to new opportunities.