Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
The central research goal of my research is to examine the concept of resiliency and sustainability within the context of resource-based communities to address the often problematic relationship(s) between resource reliance, community well-being, and adaptive capacity.
The problems I have worked on in animal science have direct implications for genetic selection, food quality (e.g. cow milk), and animal health. On the other hand, my work in understanding the structure and driving mechanisms of ecological (e.g. plant-pollinator) networks have indirect implications for ecosystem conservation, management, and restoration.
Physical processes and human activities change the landscape and increasingly these factors work in tandem on the Earth’s surface; these interactions are what inspire and drive my research.