Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
I am engaged in questions of applied landscape ecology in rural and agricultural landscapes, including changes in landscape patterns and the consequences of those changes on biodiversity, water quality, and culture.
My research uses mathematical models and computer simulation to help identify improved infectious disease prevention and control strategies in both humans and animals. Our work has a significant impact on public health and veterinary health, by strengthening planning and disease control strategies to prevent infectious disease outbreaks.