We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
My research is designed to better understand the relative risks that environmental stressors may pose to the biota of aquatic and terrestrial ecosystems with the goal of improving scientific and public understanding of those risks.
Chronic pain is a debilitating condition affecting 1 in 5 humans and animals. Our research aims to address the urgent need for the development of effective therapeutic strategies to clinically alleviate chronic pain symptoms.
I employ a quantitative approach to integrate observational, experimental and synthetic data sets, gathered by myself and others, to study this interaction of dispersal and environmental processes...
My group uses in vivo and in vitro models to ask how transcriptional regulators of the Dlx gene family influence cellular differentiation in the skeleton and craniofacial tissue patterning during vertebrate embryogenesis...
