Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
The goal of my research is to improve the life of cancer patients by identifying tools to make better treatment decisions. This can possibly improve several important aspects of the life of a cancer patient, including treatment response, the quality of life, and the overall survival following treatment.
My research is in the area of nuclear physics, using the atomic nucleus as a laboratory to understand the fundamental forces of nature, the origins of the elements in the Universe, and how simple patterns emerge from complex systems.
I study glacial deposits to reconstruct past climate change and to better understand how these deposits affect the movement of groundwater and contaminants today.
My research uses mathematical models and computer simulation to help identify improved infectious disease prevention and control strategies in both humans and animals. Our work has a significant impact on public health and veterinary health, by strengthening planning and disease control strategies to prevent infectious disease outbreaks.