Overall, our work aims to uncover novel strategies for the treatment of infectious diseases associated with fungal and bacterial pathogens in both the healthcare and agriculture sectors.
We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
The overarching goal of research in my lab is to engineer viruses to prevent, treat and cure diseases, including monogenic lung diseases, infectious diseases, and cancer.
My research uses mathematical models and computer simulation to help identify improved infectious disease prevention and control strategies in both humans and animals. Our work has a significant impact on public health and veterinary health, by strengthening planning and disease control strategies to prevent infectious disease outbreaks.
In the context of global challenges, I work in the area on communication and information for agricultural innovation and community economic development. I lead the Regional and Rural Broadband (R2B2) project.
My research program seeks to understand the underlying physiology of diseases common in horses, and how these diseases can be modified with targeted nutrition, with a focus on cartilage biology.
