The overarching goal of research in my lab is to engineer viruses to prevent, treat and cure diseases, including monogenic lung diseases, infectious diseases, and cancer.
Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
Physical processes and human activities change the landscape and increasingly these factors work in tandem on the Earth’s surface; these interactions are what inspire and drive my research.