Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
Immigrant families settling the land, quilting bees, and ploughing matches are examples of some of the social and economic topics of early Ontario that link my work to the larger expertise of this University concerning agriculture and rural communities.
My research program studies the effects of agricultural management practices (tillage and cropping systems) on the nature and dynamics of soil organic matter (SOM).