Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
My research will contribute to our fundamental understanding of the role of nutrition in disease prevention and strategies to implement change working through families.
My group uses in vivo and in vitro models to ask how transcriptional regulators of the Dlx gene family influence cellular differentiation in the skeleton and craniofacial tissue patterning during vertebrate embryogenesis...
In the context of global challenges, I work in the area on communication and information for agricultural innovation and community economic development. I lead the Regional and Rural Broadband (R2B2) project.