We study light-activated membrane proteins important in bioenergetics and vision. In our research, we combine methods of modern biophysics with techniques of molecular biology and biochemistry.
Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
Language is in a constant process of change. Understanding the hows and whys of change and the effects it has on society can help us better understand each other as human beings.
My research program is the only one in Canada that integrates economics, hydrology, and GIS to examine the cost effectiveness of landscape conservation programs.
We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
