My research focuses primarily on the genetic regulation of innate immunity in animals, with a particular focus on innate immune pattern recognition proteins.
One of my main research activities addresses the development of Electronic Design Automation (EDA) tools for Application Specific Integrated Circuits (ASIC) and Field Programmable Gate Arrays (FPGAs) which are used today in all types of applications including security systems, consumer products, medical equipment, manufacturing systems, robotics to name just a few.
Chronic pain is a debilitating condition affecting 1 in 5 humans and animals. Our research aims to address the urgent need for the development of effective therapeutic strategies to clinically alleviate chronic pain symptoms.
We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
The overarching goal of research in my lab is to engineer viruses to prevent, treat and cure diseases, including monogenic lung diseases, infectious diseases, and cancer.
