Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
I combine experiments, simulations, and theory to tackling problems like improving small hydropower systems, modeling the climate inside greenhouses, and studying airflow in both industrial processes and outdoors.
Physical processes and human activities change the landscape and increasingly these factors work in tandem on the Earth’s surface; these interactions are what inspire and drive my research.