My general research interests are interdisciplinary, and straddle the disciplines of Computer Science and Electrical Engineering. Currently, I have particular interest in developing algorithmic solutions to optimization problems that arise in both FPGA and VLSI design flows. My other active areas of research include...
Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
The overarching goal of research in my lab is to engineer viruses to prevent, treat and cure diseases, including monogenic lung diseases, infectious diseases, and cancer.
We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
My community-engaged research collaborations focus on the interplay between citizens – particularly young women and women in northern communities – and the framing and development of public policy.
I and my lab study animal welfare. We're interested in how to create good living conditions for animals kept in labs, zoos and farms; in how scientists can assess well-being objectively; and in what happens to brain and behaviour when animals are raised and kept lifelong in confining, barren enclosures.
