My group uses in vivo and in vitro models to ask how transcriptional regulators of the Dlx gene family influence cellular differentiation in the skeleton and craniofacial tissue patterning during vertebrate embryogenesis...
The goal of my research is to improve the life of cancer patients by identifying tools to make better treatment decisions. This can possibly improve several important aspects of the life of a cancer patient, including treatment response, the quality of life, and the overall survival following treatment.
Promotion of dairy cattle health, production, efficiency, and welfare not only contributes to economic viability of the dairy production sector, but also provides benefits to the consumers of milk products. These benefits include environmental sustainability, maintenance of milk nutritional quality and safety, as well as assurance that milk is sourced from animals that have been raised humanely.
We are interested in structure-function relationships of enzymes and enzyme evolution. We are studying steroid degrading enzymes from the pathogen Mycobacterium tuberculosis and other related bacteria. We are also interested in enzymes that can be used to detoxify environmental pollutants.
I combine experiments, simulations, and theory to tackling problems like improving small hydropower systems, modeling the climate inside greenhouses, and studying airflow in both industrial processes and outdoors.
Osteosarcoma is an aggressive bone cancer in dogs and people. My lab investigates the mechanisms that permit osteosarcoma cells to spread to new sites (metastasis) and survive exposure to chemotherapy (chemoresistance). Additionally, we are working on identifying biomarkers that can help predict outcomes and/or guide therapeutic decisions for patients with osteosarcoma.
